Also, counterfeits of the popular brands have emerged.
Fortunately, it has become possible to detect these drugs and their derivatives as adulterants and counterfeits by using modern sensitive and selective analytical techniques [e.g., liquid chromatography with tandem mass spectrometry, Fourier transform (FT) with near infrared spectrometry, and FT with Raman spectroscopy], although some conventional approaches have also been employed.
We critically review the literature, and present generalized strategies, including flow charts, for characterizing adulteration of PDE-5 inhibitors in HDSs, and detecting and categorizing counterfeit products.
